Probiotics and barrier function in colitis
نویسندگان
چکیده
منابع مشابه
Enhancement of Epithelial Barrier Function by Probiotics
Probiotics are microbial organisms that are administered in supplements or foods to enhance the well-being of the host. There exists substantial evidence that in a strain and dose-dependent manner, probiotics can modulate systemic and mucosal immune function, improve intestinal barrier function, alter gut microecology, and exert metabolic effects on the host. Several strains of Lactobacillus an...
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In infants, lactose ingestion induces diarrhoea that may threaten life. In children, this consumption leads to a discomfort sensation and the child learns to identify the responsible sources of that and banish them of his diet. However, in the course of teenage and moreover in adult age, it is usual and surprising to record that persons who consume again milk products do not suffer from discomf...
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Abstract Background: Pulmonary involvement in ulcerative colitis (UC) is thought to be rare. There is not a definite document about the question that "Is the lung a target organ in inflammatory bowel disease?" The aim of the present study is to compare lung function between cases with UC and healthy controls. This study will also be of interest about searching the outbreak of pulmonary functio...
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The intestinal mucosal barrier controlling the resident microbiome is dependent on a protective mucus layer generated by goblet cells, impairment of which is a hallmark of the inflammatory bowel disease, ulcerative colitis. Here, we show that IL-18 is critical in driving the pathologic breakdown of barrier integrity in a model of colitis. Deletion of Il18 or its receptor Il18r1 in intestinal ep...
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ژورنال
عنوان ژورنال: Gut
سال: 2005
ISSN: 0017-5749
DOI: 10.1136/gut.2004.060640